What is Voglibose & Metformin Tablets ?
- Voglibose:
- Voglibose is an oral antidiabetic medication that belongs to the class of drugs known as alpha-glucosidase inhibitors. It works by slowing down the digestion and absorption of carbohydrates from the digestive tract, thereby helping to control postprandial (after meal) blood sugar levels.
- Metformin:
- Metformin is another oral antidiabetic medication, belonging to the biguanide class. It primarily works by reducing the amount of glucose produced by the liver and improving the sensitivity of muscle cells to insulin, allowing better utilization of glucose by the body.
Voglibose & Metformin Tablets Uses
- Type 2 Diabetes Management:
- Voglibose & Metformin Tablets are used to manage high blood sugar levels in individuals with type 2 diabetes.
- The combination helps regulate blood glucose levels through different mechanisms: slowing carbohydrate digestion (voglibose) and reducing glucose production (metformin).
Voglibose & Metformin Tablets – Mechanism of Action and Pharmacology
- Voglibose:
- Voglibose works by inhibiting alpha-glucosidase enzymes in the digestive tract. This inhibition slows the breakdown of complex carbohydrates into glucose, delaying glucose absorption and reducing post-meal blood sugar spikes.
- Metformin:
- Metformin primarily works by decreasing the amount of glucose produced by the liver. It also improves the sensitivity of muscle cells to insulin, allowing better glucose uptake and utilization.
Voglibose & Metformin Tablets – Side-effects
- Gastrointestinal Issues:
- Nausea, vomiting, diarrhea, and stomach upset are common gastrointestinal side effects, especially with voglibose.
- Hypoglycemia (low blood sugar levels):
- Especially if taken with other antidiabetic medications.
- Abdominal Distension or Pain:
- Some individuals may experience abdominal discomfort or pain.
- Flatulence (gas):
- Voglibose can cause increased gas production.
- Headache:
- Mild to moderate headaches may occur.
