What is Tamoxifen Citrate Tablets ?
Tamoxifen citrate is a medication available in tablet form and is used for the treatment of certain types of breast cancer. It is a type of drug known as a selective estrogen receptor modulator (SERM) and is often used in hormone receptor-positive breast cancers.
Tamoxifen Citrate Tablets Uses
- Breast Cancer Treatment: Tamoxifen citrate is primarily used for the treatment of breast cancer, especially in cases where the cancer cells have estrogen receptors (ER-positive breast cancer).
- Breast Cancer Prevention: In some cases, tamoxifen may be used to reduce the risk of developing breast cancer in high-risk individuals.
Tamoxifen Citrate Tablets – Mechanism of Action and Pharmacology
Tamoxifen citrate is an antagonist of the estrogen receptor in breast tissue. It competes with estrogen for binding to estrogen receptors on the breast cancer cells. By blocking the estrogen receptors, tamoxifen inhibits the stimulatory effects of estrogen on breast tissue, preventing the growth and proliferation of estrogen-dependent breast cancer cells.
Tamoxifen is considered a selective estrogen receptor modulator because it has estrogenic effects on some tissues (like bone) and anti-estrogenic effects on others (like breast tissue). This property allows it to be beneficial in treating estrogen receptor-positive breast cancer.
Tamoxifen Citrate Tablets – Side-effects
- Nausea and Vomiting: Some individuals may experience nausea and vomiting.
- Fatigue: Tamoxifen can cause fatigue and weakness.
- Mood Swings: Mood changes, including depression, anxiety, or irritability, may occur.
