What Pantoprazole And Levosulpiride Capsules ?
Pantoprazole:Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). It works by inhibiting the proton pump in the stomach lining, which reduces the production of stomach acid. This can be helpful in conditions where excess stomach acid is causing problems, such as acid reflux, gastroesophageal reflux disease (GERD), or certain stomach ulcers.
Levosulpiride:Levosulpiride is a dopamine receptor antagonist. It primarily works on dopamine receptors in the brain and the gastrointestinal tract. In the gastrointestinal tract, it enhances motility, which can be beneficial in conditions characterized by slow or impaired movement of the digestive system.
Pantoprazole And Levosulpiride Capsules Uses
- Treatment of conditions where reduction of stomach acid is beneficial, such as:
- Gastroesophageal Reflux Disease (GERD)
- Gastric ulcers
- Duodenal ulcers
- Zollinger-Ellison syndrome (a condition where the stomach produces too much acid)
- Prevention of damage to the esophagus caused by acid reflux
- Conditions where excessive stomach acid production is a problem
Pantoprazole And Levosulpiride Capsules – Mechanism of Action and Pharmacology
Mechanism of Action:
- Pantoprazole:
- Pantoprazole is a proton pump inhibitor (PPI).
- It works by irreversibly blocking the proton pump in the stomach lining called H+/K+ ATPase. This pump is responsible for the final step in the production of stomach acid.
Levosulpiride:
- Levosulpiride is a prokinetic agent.
- It works by blocking certain receptors in the brain (specifically, dopamine D2 receptors) and also by enhancing the release of a neurotransmitter called acetylcholine in the gastrointestinal tract.
Pantoprazole And Levosulpiride Capsules – Side-effects
- Headache
- Diarrhea
- Nausea or vomiting
- Stomach pain
- Constipation
