What is Lenalidomide Capsules ?
Lenalidomide is a medication available in capsule form and is used in the treatment of various cancers and certain blood disorders. It is a derivative of thalidomide and belongs to a class of drugs known as immunomodulatory agents.
Lenalidomide Capsules Uses
- Multiple Myeloma: Lenalidomide is primarily used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow.
- Myelodysplastic Syndromes (MDS): Lenalidomide is also used for the treatment of myelodysplastic syndromes, a group of disorders characterized by abnormal production of blood cells in the bone marrow.
- Mantle Cell Lymphoma: Lenalidomide is used for the treatment of mantle cell lymphoma, a type of non-Hodgkin’s lymphoma.
- Follicular Lymphoma: In certain cases, lenalidomide may be used for the treatment of follicular lymphoma, another type of non-Hodgkin’s lymphoma.
Lenalidomide Capsules – Mechanism of Action and Pharmacology
Lenalidomide is an immunomodulatory drug that has multiple mechanisms of action. It helps in inhibiting the growth of cancer cells and enhances the immune response against cancer.
- Immunomodulation: Lenalidomide modulates the immune system by enhancing the activity of certain immune cells (T cells and natural killer cells) and suppressing the activity of inflammatory cytokines.
- Anti-Angiogenesis: Lenalidomide inhibits the growth of new blood vessels, a process called angiogenesis, which is essential for tumor growth and spread.
- Anti-Proliferation: Lenalidomide inhibits the proliferation of cancer cells by interfering with their cell cycle and inducing apoptosis (programmed cell death).
Lenalidomide Capsules – Side-effects
- Fatigue: Fatigue and weakness are common side effects.
- Nausea and Vomiting: Some individuals may experience nausea and vomiting.
- Diarrhea: Diarrhea is another common side effect of lenalidomide.
