Glipizide Tablets

What is Glipizide Tablets ?

Glipizide is an oral antidiabetic medication used in the management of type 2 diabetes. It belongs to the class of drugs known as sulfonylureas. Glipizide helps to lower blood sugar levels by stimulating the pancreas to produce more insulin, a hormone that facilitates the uptake of glucose by cells in the body.

Type 2 Diabetes Management:
Glipizide tablets are primarily used to manage high blood sugar levels in people with type 2 diabetes.
It helps control blood glucose levels and prevent complications associated with uncontrolled diabetes.

Insulin Stimulation:
- Glipizide works by binding to specific receptors on the beta cells of the pancreas. This binding stimulates the pancreas to release more insulin into the bloodstream.
- Insulin is a hormone that facilitates the uptake and utilization of glucose by cells, reducing blood sugar levels.
Blocking Potassium Channels:
- Glipizide, like other sulfonylureas, also blocks ATP-sensitive potassium channels in the beta cells of the pancreas. This blockade leads to calcium influx and subsequent insulin release.

Hypoglycemia (Low Blood Sugar):
- Glibenclamide can cause low blood sugar levels (hypoglycemia). Symptoms may include shakiness, dizziness, sweating, confusion, and, in severe cases, loss of consciousness.
Gastrointestinal Issues:
- Nausea, vomiting, diarrhea, and stomach upset are common gastrointestinal side effects.
Skin Reactions:
- Skin reactions such as rash or itching may occur in some individuals.
Weight Gain:
- Glibenclamide may cause weight gain in some people.
Allergic Reactions:
- Allergic reactions to glibenclamide are rare but can include symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing.
Liver Issues:
- Glibenclamide can affect liver function in rare cases, leading to symptoms like yellowing of the skin/eyes, dark urine, or persistent nausea/vomiting.