What is Gliclazide Tablets ?
Gliclazide is a medication commonly used to treat type 2 diabetes. It belongs to a class of drugs called sulfonylureas, which work by stimulating the pancreas to produce more insulin. Insulin is a hormone that helps regulate blood sugar levels.
Gliclazide Tablets Uses
- Type 2 Diabetes: Gliclazide is prescribed to individuals with type 2 diabetes who are unable to control their blood sugar levels through diet and exercise alone.
- Lowering Blood Sugar Levels: Gliclazide helps lower elevated blood sugar levels by stimulating the pancreas to release more insulin. This helps the body utilize glucose more effectively.
- Preventing Complications: By regulating blood sugar levels, Gliclazide helps reduce the risk of complications associated with uncontrolled diabetes.
Gliclazide Tablets – Mechanism of Action and Pharmacology
- Stimulation of Insulin Release: Gliclazide primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that plays a crucial role in regulating blood sugar levels. It promotes the uptake of glucose from the bloodstream into cells, especially in muscles and the liver, where it can be used for energy.
- Closing of ATP-Sensitive Potassium Channels: Gliclazide acts by binding to and inhibiting ATP-sensitive potassium channels in the beta cells of the pancreas. These channels are normally responsible for maintaining the cell’s electrical potential
Gliclazide Tablets – Side-effect
- Diarrhea or Constipation: Some individuals may experience changes in bowel habits.
- Weight Gain: It’s possible for some people to experience weight gain while taking Gliclazide.
- Skin Reactions: In rare cases, allergic skin reactions like rash or itching may occur.
