What is Doxofylline Tablets ?
Doxofylline is a medication that belongs to a class of drugs called bronchodilators. It is used in the treatment of respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). Doxofylline works by relaxing and widening the airways in the lungs, making it easier to breathe.
Doxofylline is available in various forms, including tablets and syrups. The tablets are typically taken orally, and the dosage and frequency of administration are usually prescribed by a healthcare provider based on the individual’s specific condition.
Doxofylline Tablets Uses
- Asthma: Doxofylline helps to relieve symptoms of asthma, such as wheezing, shortness of breath, and coughing. It works by relaxing the muscles around the airways, making it easier for air to flow in and out.
- Chronic Obstructive Pulmonary Disease (COPD): Doxofylline may be prescribed to people with COPD, a group of lung diseases that includes chronic bronchitis and emphysema. It can help improve breathing in individuals with these conditions.
Doxofylline Tablets – Mechanism of Action and Pharmacology
- Phosphodiesterase (PDE) Inhibition: Doxofylline primarily works by inhibiting the enzyme phosphodiesterase (PDE), specifically PDE4. PDE4 is responsible for breaking down cyclic adenosine monophosphate (cAMP), which is an important signaling molecule in various cellular processes, including those involved in bronchodilation.
- Bronchodilation: By inhibiting PDE4 and preventing the breakdown of cAMP, doxofylline leads to increased levels of cAMP in smooth muscle cells of the airways. This, in turn, results in relaxation of the bronchial smooth muscles, leading to bronchodilation. This is particularly beneficial for people with conditions like asthma and COPD, where bronchoconstriction (narrowing of the airways) is a significant problem.
- Anti-inflammatory Effects: Doxofylline also has anti-inflammatory properties, which can be beneficial in the treatment of respiratory conditions. It can reduce the release of inflammatory mediators from cells involved in the immune response.
Doxofylline Tablets – Composition and Active Ingredients
Doxofylline is a medication used to treat respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It belongs to a class of drugs known as xanthines, which work by relaxing the muscles in the airways and improving airflow to the lungs.
The active ingredient in Doxofylline tablets is, unsurprisingly, doxofylline itself. It is a xanthine derivative that is structurally related to theophylline, another commonly used medication for respiratory conditions.
Doxofylline is typically available in tablet form, and each tablet contains a specific amount of doxofylline as the active ingredient. The dosage and formulation of the tablets may vary depending on the specific brand and manufacturer.
Doxofylline Tablets – Side-effect
- Nausea or upset stomach: Some people may experience gastrointestinal discomfort, including nausea or an upset stomach.
- Headache: Headaches can occur in some individuals taking Doxofylline.
- Insomnia or difficulty sleeping: Due to its stimulating effects, Doxofylline can sometimes cause difficulty falling asleep.
