What is Aceclofenac + Paracetamol Tablets ?
- Aceclofenac (100 mg): Aceclofenac works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals in the body that mediate pain, inflammation, and fever. By inhibiting COX, Aceclofenac reduces the production of prostaglandins, leading to a decrease in pain and inflammation.
- Paracetamol (500 mg): Paracetamol primarily works by inhibiting the enzyme cyclooxygenase in the central nervous system (brain and spinal cord). It helps to reduce the production of prostaglandins in the brain, which are involved in the perception of pain and regulation of body temperature.
Aceclofenac + Paracetamol Tablets Tablet Uses
- Pain Relief: Aceclofenac and Paracetamol are combined to provide relief from mild to moderate pain, including headache, muscle aches, dental pain, and menstrual cramps.
- Inflammation Reduction: The combination is used to alleviate inflammation associated with conditions such as arthritis (rheumatoid arthritis, osteoarthritis) and ankylosing spondylitis.
Aceclofenac + Paracetamol 500 mg Tablets Tablet – Mechanism of Action and Pharmacology
Combining Aceclofenac and Paracetamol in a single tablet, the goal is to achieve a better pain relief and anti-inflammatory effect through the dual mechanisms of action: inhibition of COX by Aceclofenac, and central action on COX-3 by Paracetamol. This combination can be especially effective for conditions associated with both pain and inflammation, providing relief to the patient. However, it’s important to follow the prescribed dosage and guidelines to avoid any potential side effects or adverse reactions. Always consult a healthcare professional for accurate and personalized information regarding medications and their mechanisms of action.
Aceclofenac 100 mg + Paracetamol 500 mg Tablet – Side-effects
- Common side effects may include gastrointestinal discomfort (nausea, indigestion, etc.), dizziness, headache, and skin rash.
- Serious side effects such as gastric ulceration, liver or kidney problems, or allergic reactions are rare but possible and should be reported to a healthcare provider.
