What is Tenoxicam Tablets ?
Tenoxicam is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain, inflammation, and swelling in various conditions such as arthritis and other musculoskeletal disorders. It belongs to a class of medications known as oxicams.
Tenoxicam works by inhibiting the production of certain chemicals in the body called prostaglandins. Prostaglandins are substances that play a role in pain, inflammation, and fever. By blocking their production, Tenoxicam helps to alleviate pain and reduce inflammation.
Tenoxicam Tablets Uses
- Arthritis: Tenoxicam is often prescribed for both osteoarthritis and rheumatoid arthritis. It helps to reduce pain and inflammation in the joints.
- Musculoskeletal Disorders: It can be used to treat a range of musculoskeletal disorders such as tendonitis, bursitis, and other conditions involving the muscles and/or bones.
- Pain Relief: Tenoxicam can be used for the short-term relief of mild to moderate pain, such as that associated with injuries, dental procedures, or menstrual cramps.
- Post-Surgical Pain: It may be prescribed after certain types of surgery to manage post-operative pain and inflammation.
- Gout: Tenoxicam may be used as part of the treatment plan for gout, a type of arthritis caused by the buildup of uric acid crystals in the joints.
- Other Inflammatory Conditions: Tenoxicam may be prescribed for various inflammatory conditions, including conditions affecting the soft tissues, like tendinitis.
Tenoxicam Tablets – Mechanism of Action and Pharmacology
- Inhibition of COX-1 and COX-2: Tenoxicam inhibits both COX-1 and COX-2 enzymes. COX-1 is constitutively expressed in many tissues and is involved in the production of prostaglandins that play a role in various physiological processes, including maintaining the integrity of the stomach lining and promoting platelet aggregation (clotting). COX-2, on the other hand, is primarily induced in response to inflammation and is responsible for producing prostaglandins that mediate pain, fever, and inflammation.
- Reduction of Prostaglandin Production: By inhibiting COX-1 and COX-2, Tenoxicam decreases the production of prostaglandins. Prostaglandins are lipid compounds that act as signaling molecules in the body and are involved in processes like pain sensation, inflammation, and fever.
- Anti-inflammatory Effects: The reduction in prostaglandin production leads to decreased inflammation in the affected tissues. This is particularly useful in conditions like arthritis, where inflammation is a major contributor to pain and joint damage.
- Analgesic Effects: By blocking prostaglandin production, Tenoxicam also helps to alleviate pain associated with various conditions.
Tenoxicam Tablets – Side-effect
- Nausea
- Indigestion or heartburn
- Abdominal pain or discomfort
- Diarrhea or constipation
- Gastric ulcers or bleeding (in rare cases, especially with long-term use)
