Diclofenac Sodium Paracetamol Table

What is Diclofenac Sodium Paracetamol Table ?

Diclofenac Sodium:
- Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX). COX is involved in the production of prostaglandins, which are substances in the body that mediate pain and inflammation.
- By inhibiting COX, diclofenac sodium helps to reduce pain, inflammation, and fever.
Paracetamol (Acetaminophen):
- Paracetamol is a commonly used analgesic and antipyretic medication. Its exact mechanism of action is not completely understood, but it is believed to work by inhibiting an enzyme in the central nervous system that is involved in the production of prostaglandins.

Musculoskeletal Pain:
- This includes conditions like back pain, neck pain, joint pain, muscle strains, and sprains.
Headache and Migraine:
- It can be used to alleviate mild to moderate headaches, including tension headaches and migraines.
Dental Pain:
- It may be prescribed after dental procedures or for conditions like toothaches.
Post-Operative Pain:
- It can help manage pain following surgical procedures.
Inflammatory Conditions:
- Conditions like osteoarthritis and rheumatoid arthritis, where there is pain and inflammation in the joints.
Menstrual Pain:
- It may be used to relieve the pain associated with menstrual cramps.
Fever:
- Paracetamol is an effective antipyretic and is used to lower elevated body temperature in cases of fever.

Diclofenac Sodium:
- Mechanism of Action:
  - Diclofenac sodium is classified as a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting the activity of an enzyme called cyclooxygenase (COX).
  - COX is involved in the production of prostaglandins, which are chemicals in the body that mediate pain, inflammation, and fever.
  - By inhibiting COX, diclofenac sodium reduces the production of prostaglandins, leading to decreased pain, inflammation, and fever.
- Pharmacology:
  - Absorption: Diclofenac sodium is absorbed from the gastrointestinal tract after oral administration.
  - Distribution: It is distributed widely throughout the body, including areas where inflammation may be present.
  - Metabolism: Diclofenac undergoes extensive metabolism in the liver.
  - Excretion: The metabolites are primarily eliminated in the urine.
Paracetamol (Acetaminophen):
- Mechanism of Action:
  - The exact mechanism of action of paracetamol is not completely understood. However, it is believed to work by inhibiting an enzyme known as COX in the central nervous system (specifically COX-2), which reduces the production of prostaglandins in the brain.
  - Unlike NSAIDs, it has limited anti-inflammatory effects, but it is an effective analgesic (pain reliever) and antipyretic (fever reducer).