What is Temozolomide Capsules ?
Temozolomide is an oral chemotherapy drug available in capsule form, and it is used in the treatment of certain types of brain tumors, specifically glioblastoma multiforme (GBM) and anaplastic astrocytoma.
Temozolomide Capsules Uses
- Glioblastoma Multiforme (GBM): Temozolomide is a standard treatment for newly diagnosed glioblastoma multiforme, a highly aggressive type of brain tumor.
- Anaplastic Astrocytoma: Temozolomide is also used in the treatment of anaplastic astrocytoma, another type of brain tumor.
Temozolomide Capsules – Mechanism of Action and Pharmacology
Temozolomide is an alkylating agent that belongs to the class of chemotherapy drugs. It works by modifying and damaging the DNA in cancer cells, particularly by adding methyl groups to the DNA molecule. This modification interferes with DNA replication and leads to cell death, inhibiting the growth and spread of cancer cells.
Temozolomide is unique in its ability to cross the blood-brain barrier, allowing it to effectively target brain tumors.
Temozolomide Capsules – Side-effects
- Loss of Appetite: Chemotherapy can lead to a decreased appetite and weight loss.
- Constipation or Diarrhea: Changes in bowel habits, including constipation or diarrhea, may occur.
- Hair Loss: Temozolomide can cause hair loss, although it is typically less severe than with some other chemotherapy drugs.
