What is Sorafenib Tosylate Tablets ?
Sorafenib tosylate is a targeted therapy medication that is available in tablet form. It is used to treat certain types of cancer, primarily advanced renal cell carcinoma (kidney cancer) and hepatocellular carcinoma (a type of liver cancer). Sorafenib tosylate belongs to the class of drugs known as tyrosine kinase inhibitors.
Sorafenib Tosylate Tablets Uses
- Renal Cell Carcinoma (RCC): Sorafenib tosylate is used for the treatment of advanced renal cell carcinoma, a type of kidney cancer.
- Hepatocellular Carcinoma (HCC): It is also indicated for the treatment of hepatocellular carcinoma, which is a common type of liver cancer.
Sorafenib Tosylate Tablets – Mechanism of Action and Pharmacology
Sorafenib is a multikinase inhibitor that interferes with the growth and spread of cancer cells by targeting specific proteins and enzymes involved in tumor cell signaling, angiogenesis (formation of blood vessels within the tumor), and cell proliferation. It inhibits multiple kinases, including vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), and RAF kinases. By inhibiting these pathways, sorafenib suppresses tumor growth and angiogenesis.
Sorafenib Tosylate Tablets – Side-effects
- Fatigue: Fatigue and weakness are common side effects.
- Hand-Foot Skin Reaction: This can cause redness, tenderness, and peeling of the skin on the palms of the hands and soles of the feet.
