What is Chlorambucil Tablets ?
Chlorambucil is a chemotherapy drug that belongs to the class of alkylating agents. It is available in tablet form and is used to treat certain types of cancer, particularly chronic lymphocytic leukemia (CLL), Hodgkin’s lymphoma, and non-Hodgkin’s lymphoma. Chlorambucil works by interfering with the DNA in cancer cells, ultimately inhibiting their growth and reproduction.
Chlorambucil Tablets Uses
- Chronic Lymphocytic Leukemia (CLL): Chlorambucil is commonly used to treat CLL, a type of cancer that affects white blood cells.
- Hodgkin’s Lymphoma: Chlorambucil may be used in the treatment of Hodgkin’s lymphoma, a cancer of the lymphatic system.
- Non-Hodgkin’s Lymphoma: Chlorambucil is also used to treat various types of non-Hodgkin’s lymphomas, which are cancers that affect the lymphatic system.
Chlorambucil Tablets – Mechanism of Action and Pharmacology
Chlorambucil belongs to the alkylating agent class of chemotherapy drugs. Alkylating agents work by forming covalent bonds with DNA molecules in cells, disrupting the structure of DNA and preventing the cancer cells from dividing and growing. Chlorambucil specifically affects the DNA in cancer cells, inhibiting their ability to replicate and ultimately leading to cell death.
Chlorambucil Tablets – Side-effects
- Fatigue: Many individuals experience fatigue and weakness during chemotherapy treatment.
- Loss of Appetite: Chemotherapy can lead to a decreased appetite and weight loss.
- Hair Loss: Chlorambucil can cause hair loss, although it is typically less severe than with some other chemotherapy drugs.
