Pantoprazole Domperidone Tablets

What is Pantoprazole Domperidone Tablets ?

• Pantoprazole: It belongs to a class of medications known as proton pump inhibitors (PPIs). Pantoprazole works by reducing the amount of acid produced in the stomach. It is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions where excessive stomach acid production is a problem.
• Domperidone: This medication is a type of dopamine receptor antagonist. It works by blocking dopamine receptors in the brain and in the upper digestive system. Domperidone is often used to help relieve symptoms like nausea and vomiting, and it may also be used to aid in the movement of food through the digestive system.

Pantoprazole Domperidone Tablets Uses

• Gastroesophageal Reflux Disease (GERD): This is a condition where stomach acid flows back into the esophagus, leading to symptoms like heartburn, regurgitation, and difficulty swallowing. Pantoprazole helps reduce the production of stomach acid, while domperidone can help alleviate associated symptoms like nausea and vomiting.
• Peptic Ulcers: These are open sores that develop on the lining of the stomach or the upper part of the small intestine. Pantoprazole helps in healing and preventing further ulcers by reducing stomach acid production.
• Zollinger-Ellison Syndrome: This is a rare condition where the stomach produces too much acid. Pantoprazole is often used to manage this condition.
• Nausea and Vomiting: Domperidone is primarily used to relieve symptoms of nausea and vomiting, which can be caused by various factors including certain medications, surgery, or gastrointestinal disorders.

Pantoprazole Domperidone Tablet – Mechanism of Action and Pharmacology

Pantoprazole:

• Mechanism of Action:
  • Pantoprazole is a proton pump inhibitor (PPI).
  • It inhibits the action of proton pumps in the stomach lining, reducing stomach acid production.
• Pharmacology:
  • It’s absorbed in the small intestine and converted into its active form in the stomach’s acidic environment.
  • It binds irreversibly to proton pumps, providing long-lasting suppression of acid production.

Domperidone:

• Mechanism of Action:
  • Domperidone is a dopamine receptor antagonist.
  • It blocks dopamine receptors in the brain and upper digestive system, leading to increased contractions in the digestive tract.
• Pharmacology:
  • It’s absorbed in the gastrointestinal tract and primarily acts on peripheral dopamine receptors.
  • It helps move food through the digestive system efficiently.

Pantoprazole Domperidone Tablets – Side-effects

• ommon Side Effects:
  • Headache
  • Nausea
  • Diarrhea
  • Stomach pain
  • Constipation
• Less Common Side Effects:
  • Dizziness
  • Joint pain
  • Rash