What is Flunarizine Tablets ?
- Flunarizine is a medication primarily used to prevent migraine headaches. It is available in tablet form and belongs to the class of drugs known as calcium channel blockers.
Flunarizine Tablets Uses
- Migraine Prevention:
- Flunarizine tablets are used for the prevention of migraine headaches, including reducing the frequency and intensity of migraines in individuals prone to these types of headaches.
- Vertigo and Vestibular Disorders:
- Flunarizine is also used to manage vertigo and various vestibular disorders, which affect balance and spatial orientation.
Flunarizine Tablets – Mechanism of Action and Pharmacology
- Calcium Channel Blockade:
- Flunarizine works by blocking calcium channels, particularly those in the smooth muscle cells of blood vessels and in the brain.
- By blocking calcium channels, it reduces the influx of calcium into the cells, leading to relaxation of blood vessel walls and improved blood flow, which can help prevent migraines.
- Anti-migraine Effect:
- The calcium channel blocking activity of Flunarizine is thought to reduce the hyperexcitability of neurons and dampen the spread of the migraine process in the brain.
Flunarizine Tablets – Side-effects
- Drowsiness or Fatigue:
- Flunarizine may cause drowsiness or fatigue, affecting your ability to concentrate or operate machinery.
- Weight Gain:
- Some individuals may experience weight gain as a side effect.
- Depression or Mood Changes:
- Flunarizine can cause mood changes or depressive symptoms in some individuals.
- Extrapyramidal Symptoms:
- These are movement disorders that may manifest as tremors, rigidity, or involuntary movements. This side effect is rare.
- Gastrointestinal Issues:
- Nausea, vomiting, or stomach upset may occur.
- Sleep Disturbances:
- Flunarizine can cause sleep disturbances or insomnia in some individuals.
