What is Cetirizine Tablets ?
- Cetirizine is an antihistamine medication primarily used to relieve allergy symptoms such as sneezing, runny or stuffy nose, itching or watery eyes, and itching or swelling caused by chronic urticaria (hives). It belongs to the second-generation antihistamine class and is available in various forms, including tablets, syrup, and chewable tablets.
Cetirizine Tablets Uses
- Allergic Rhinitis:
- Cetirizine tablets are commonly used to treat allergic rhinitis, which includes symptoms like sneezing, runny or stuffy nose, and itching or watery eyes due to allergens like pollen, dust, pet dander, etc.
- Chronic Urticaria (Hives):
- Cetirizine is also used to relieve itching and swelling caused by chronic urticaria (hives), a condition characterized by the appearance of red, itchy welts on the skin.
Cetirizine Tablets – Mechanism of Action and Pharmacology
- Histamine Receptor Blockade:
- Cetirizine works by blocking the effects of histamine, a natural substance in the body that is released during an allergic reaction.
- It specifically targets and blocks histamine H1 receptors, reducing the symptoms associated with allergies and allergic reactions.
- Selective Antagonism:
- Cetirizine is a selective antagonist for histamine H1 receptors, meaning it competes with histamine for binding to these receptors, thereby preventing histamine from causing its characteristic allergic response.
Cetirizine Tablets – Side-effects
- Drowsiness (mild):
- Although cetirizine is a second-generation antihistamine and is less sedating than first-generation antihistamines, it can still cause mild drowsiness in some individuals.
- Dry Mouth or Throat:
- Cetirizine may cause dryness of the mouth or throat.
- Headache:
- Some individuals may experience mild to moderate headaches.
- Stomach Pain or Upset:
- Stomach discomfort or upset may occur in some cases.
- Dizziness:
- Mild dizziness might be experienced by some individuals.
- Nausea:
- Nausea is a rare side effect but can occur.
